Efficiency of Essential Oils as Antifungal Agents against Aspergillus fumigatus KY026061 Causing Allergic Bronchopulmonary Aspergillosis (ABPA)

Document Type : Regular issue (Original Article)

Authors

Botany Department, Faculty of Science, Tanta University, Tanta, Egypt

Abstract

ALLERGIC bronchopulmonary aspergillosis (ABPA) and invasive aspergillosis are often found in severely immuno-suppressed patients and are characterized by invasion of conidia of Aspergillus fumigatus into blood vessels which can result in dissemination to other organs. Aspergilloma is a fungal ball that develops in previous cavity lung lesions. Essential oils have been used as antifungal agents. Inhalation of vapors of the essential oils kill invaders attached to the inner respiratory lining and work synergistically with the body defenses. In this study, (Ginger) and Cinnamomum camphora (Camphor) with inhibition zones ranging from
11to 31mm. Treatment of A. fumigatus with cinnamon essential oil lead to external changes, irregular cell shape and disintegration of fungus cell wall as detected under transmission electron microscope and then make analysis by GC-MS.

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