El-Chaghaby, G., Mohammed, F., Rashad, S., Uysal, I., Koçer, O., Lekesiz, &., Doğan, M., Şabik, A., Sevindik, M. (2024). Genus Hypericum: General Properties, Chemical Contents and Biological Activities. Egyptian Journal of Botany, 64(1), 1-26. doi: 10.21608/ejbo.2023.217116.2378
Ghadir A. El-Chaghaby; Falah S. Mohammed; Sayed Rashad; Imran Uysal; Oğuzhan Koçer; Ömer Lekesiz; Mehmet Doğan; Ali E. Şabik; Mustafa Sevindik. "Genus Hypericum: General Properties, Chemical Contents and Biological Activities". Egyptian Journal of Botany, 64, 1, 2024, 1-26. doi: 10.21608/ejbo.2023.217116.2378
El-Chaghaby, G., Mohammed, F., Rashad, S., Uysal, I., Koçer, O., Lekesiz, &., Doğan, M., Şabik, A., Sevindik, M. (2024). 'Genus Hypericum: General Properties, Chemical Contents and Biological Activities', Egyptian Journal of Botany, 64(1), pp. 1-26. doi: 10.21608/ejbo.2023.217116.2378
El-Chaghaby, G., Mohammed, F., Rashad, S., Uysal, I., Koçer, O., Lekesiz, &., Doğan, M., Şabik, A., Sevindik, M. Genus Hypericum: General Properties, Chemical Contents and Biological Activities. Egyptian Journal of Botany, 2024; 64(1): 1-26. doi: 10.21608/ejbo.2023.217116.2378
Genus Hypericum: General Properties, Chemical Contents and Biological Activities
1Bioanalysis Laboratory, Regional Center for Food and Feed, Agricultural Research Center, Giza, Egypt.
2Department of Biology, Faculty of Science, University of Zakho, Duhok, 42001, Iraq.
3Department of Food Processing, Bahçe Vocational School, University of Osmaniye Korkut Ata, Osmaniye, 80000, Turkey.
4Department of Pharmacy Services, Vocational School of Health Services, University of Osmaniye Korkut Ata, Osmaniye, 80000, Turkey.
5Department of Biology, Faculty of Science and Literature, University of Osmaniye Korkut Ata, Osmaniye, 80000, Turkey.
6Department of Chemistry and Chemical Processing Technologies, Bahçe Vocational School, University of Osmaniye Korkut Ata, Osmaniye, 80000, Turkey
Abstract
Plants of the Hypericum L. genus are widely distributed with several identified species all over the world. In addition to their nutritional properties, plants of the Hypericum L. genus are also noteworthy for their pharmacological properties. These plants have long been a part of traditional medicine in many nations. The present work presents a brief review about Hypericum species; their general characteristics, bioactivities, and phytochemical composition as reported in the published literature. From the researches reviewed during the current work, it was confirmed that Hypericum species contain high levels of antioxidant, antimicrobial, and anticancer activities in terms of biological activity which enables the species to be commonly used in the fight against diseases. The plant species were also reported to contain appreciate concentrations of important minerals including iron, zinc, calcium and sodium. Many biological activities such as antihyperglycemic, anticancer, antimicrobial, anti-inflammatory, antioxidant, hepatoprotective activities, acetylcholinesterase and monoamine oxidase inhibitory properties are exhibited by Hypericum species. Additionally, it has been concluded that the most commonly reported chemical bioactive compounds found in Hypericum species are caryophyllene (1), caryophyllene oxide (2), germacrene-D (3), limonene (4), spathulenol (5), β-pinene (6), α-pinene (7), γ-muurolene (8), β-selinene (9), and δ-cadinene (10). Taking all of this information into account, it is clear that Hypericum plant species offer potential medicinal benefits in addition to their nutritional worth.
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