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Egyptian Journal of Botany
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Volume Volume 65 (2025)
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Al-Sarraj, F. (2025). Promising antimicrobial activity of Saudi honey against seventeen multidrug resistant P. aeruginosa strains. Egyptian Journal of Botany, 65(1), 390-403. doi: 10.21608/ejbo.2024.336703.3079
Faisal Al-Sarraj. "Promising antimicrobial activity of Saudi honey against seventeen multidrug resistant P. aeruginosa strains". Egyptian Journal of Botany, 65, 1, 2025, 390-403. doi: 10.21608/ejbo.2024.336703.3079
Al-Sarraj, F. (2025). 'Promising antimicrobial activity of Saudi honey against seventeen multidrug resistant P. aeruginosa strains', Egyptian Journal of Botany, 65(1), pp. 390-403. doi: 10.21608/ejbo.2024.336703.3079
Al-Sarraj, F. Promising antimicrobial activity of Saudi honey against seventeen multidrug resistant P. aeruginosa strains. Egyptian Journal of Botany, 2025; 65(1): 390-403. doi: 10.21608/ejbo.2024.336703.3079

Promising antimicrobial activity of Saudi honey against seventeen multidrug resistant P. aeruginosa strains

Article 35, Volume 65, Issue 1, January 2025, Page 390-403  XML PDF (1.38 MB)
Document Type: Regular issue (Original Article)
DOI: 10.21608/ejbo.2024.336703.3079
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Author
Faisal Al-Sarraj email
a Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
Abstract
Pseudomonas aeruginosa, a significant drug-resistant pathogen, is a major issue in hospitals, especially the wide range infection in intensive care units, due to its complicated antibiotic resistance mechanisms and protective biofilms formation. The study aimed at evaluation the potential antibacterial activity of Sidr, Talh, and Sommra honey obtained from Al-Bahha region, Saudi Arabia against 17 drug-resistant P. aeruginosa strains collected from patients of various ages at King Abdulaziz University Hospital. The identification and antimicrobial susceptibility testing were performed throughout disk diffusion and Vitek 2 automate system, and genetic manipulation. Our results showed that Talh, Sidr and Sommra honey was exhibited high antimicrobial efficiency against bacterial infection, also indicated the synergistic efficiency of honey supplementation in fighting a drug-resistant P. aeruginosa strains with synthetic antibiotics. This study outcomes pointed out the crucial role of natural honey supplementation in healthcare and bacterial infections control, which in turn is consistent with the Saudi Arabia's goals for improving public health and combating infectious diseases. These results need a further exploration into honey's potential as a natural approach to managing infections resistant to antibiotics and highlight its significance in developing novel healthcare solutions that align with the Kingdom of Saudi Arabia's objectives for advancing medical science.
Keywords
Pseudomonas aeruginosa; a drug-resistant bacteria; honey; Vitek 2; molecular identification 16S rDNA; phylogenetic tree
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