Atef, N., Badr, H., Amer, W., Abd EL-Raheem, L. (2017). Efficiency of Egyptian Plant Extracts on the Antibiotic Susceptible and Resistant Pathogenic bacterial Isolates. Egyptian Journal of Botany, 57(3), 457-467. doi: 10.21608/ejbo.2017.1141.1105
N. Atef; H. Badr; Wafaa Amer; L. F. Abd EL-Raheem. "Efficiency of Egyptian Plant Extracts on the Antibiotic Susceptible and Resistant Pathogenic bacterial Isolates". Egyptian Journal of Botany, 57, 3, 2017, 457-467. doi: 10.21608/ejbo.2017.1141.1105
Atef, N., Badr, H., Amer, W., Abd EL-Raheem, L. (2017). 'Efficiency of Egyptian Plant Extracts on the Antibiotic Susceptible and Resistant Pathogenic bacterial Isolates', Egyptian Journal of Botany, 57(3), pp. 457-467. doi: 10.21608/ejbo.2017.1141.1105
Atef, N., Badr, H., Amer, W., Abd EL-Raheem, L. Efficiency of Egyptian Plant Extracts on the Antibiotic Susceptible and Resistant Pathogenic bacterial Isolates. Egyptian Journal of Botany, 2017; 57(3): 457-467. doi: 10.21608/ejbo.2017.1141.1105
Efficiency of Egyptian Plant Extracts on the Antibiotic Susceptible and Resistant Pathogenic bacterial Isolates
1Botany and Microbiology Department, Faculty of Science, Cairo University, Cairo, Egypt
2Bacteriology Department, Animal Health Research Institute, Cairo, Egypt
3Medical Lab., Private Sector. Cairo, Egypt.
Abstract
S UCCESSIVE leaf extracts of three Egyptian plant species: Datura stramonium L., Withania somnifera (L.) Dun. in DC. and Ziziphus spina-christi (L.)Willd were studied for their antimicrobial activity against susceptible and Multi-Drug Resistant (MDR) bacteria isolated from chickens. Four bacterial spp. namely: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella sp. were isolated from 463 different chicken samples. The sensitivity of these bacterial isolates was tested against 11 types of antibiotics: Ampicillin, Amoxicillin, Cefaclor, Gentamicin, Amikacin, Tobramycin, Ciprofloxacin, Nalidixic acid, Erythromycin, Tetracycline and Vancomycin. The isolates of E. coli, S. aureus, P.aureugenosa and Salmonella sp. showed notable bacterial resistance against the used antibiotics with percentages: (68.18%), (59.09%), (54.54%) and (54.54%); respectively. Chloroform extract of Datura stramonium showed the highest antibacterial activity against all the studied bacterial isolates with MICs values varying from 75.0 to 0.037 mg/ml. In conclusion, the present work indicated the potentiality of Datura stramonium chloroform extract as a promising national source for drug industry to produce antibiotics to be used against pathogenic multidrug resistant bacteria.
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